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Editorial |
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e- SQUARE-
Readers' Choice
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Dear Doctor:
Hope you are enjoying "e-SQUARE". We are
trying to provide you with the latest and updated topics of
your interest. In this issue we are focusing on New Cause of Arthritis!,
TV Enhances Smoking! , Stress & Diabetes, New Transplant Technique,
Aspirin & Pregnancy, Pain Relief in Osteoporosis.
Please send your feedback on our
information service to you. Click on to your reply mode.
Wish you all a happy and
prosperous life.
Yours sincerely,
Editorial Team
The views expressed in this
publication do not necessarily reflect those of its editor or
SQUARE PHARMACEUTICALS
LTD.
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New Cause
of Arthritis! |
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Glycosaminoglycans (GAGs) may cause
arthritis Back to
Features |
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New research shows carbohydrates that
originate in the body, called glycosaminoglycans (GAGs), may
cause arthritis. Researchers have linked GAGs to the defense
system in the body that causes inflammation. While the cause
of arthritis has been a mystery, this new finding may shed
light on the origin of the crippling disease. GAGs are found
in joint cartilage, joint fluid, connective tissue, and skin.
Researchers examined GAG in mice with arthritic symptoms.
Study shows that rheumatoid arthritis may result from the
body's mishandling of its own carbohydrates that, under normal
circumstances, would not be interpreted as a threat.
Researchers found that inflammatory cells that accumulate in
arthritic joints attach themselves directly to the
glycosaminoglycans. This accumulation of cells leads to
painful inflammation and swelling in the affected tissue. By
examining human tissue taken from arthritic sufferers, the
researchers were able to find the same glycosaminoglycans
hindering cells in humans
SOURCE: American
Chemical Society national meeting in Boston, Aug. 18 - 22,
2002
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TV Enhances
Smoking! |
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Smoking linked to watching
TV
Back to
Features |
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Turning off the television could prevent
young people from lighting up. A new study finds the more an
adolescent watches television, the more likely they are to
start smoking. Researchers looked at whether adolescents who
watched more television were more likely to start smoking.
They used information from a national survey that gathered
data on television viewing in 1990 and 1992 among youth ages
10 to 15 years. They also examined other risk factors such as
weight, ethnicity, IQ, household income level and household
structure. Among the adolescents in the study, smoking
increased from about 5 percent in 1990 to more than 12 percent
in 1992. Researchers say those who watched five hours or more
of TV per day were nearly six times more likely to start
smoking than those who watched less than two hours a day.
Researchers say their study clearly shows television viewing
is associated with smoking among young
people.
SOURCE:
Pediatrics, 2002; 110:505-508
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Stress &
Diabetes |
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Stress relief improves diabetes
health
Back to
Features |
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A stress management program may help people
with type 2 diabetes improve their blood sugar level, a new
study shows. Researchers studied 108 patients, ages 30 or
older, with type 2 diabetes. Patients participated in a
diabetes education program with or without stress management
training. Researchers measured the patients' stress levels and
hemoglobin A1C levels throughout the year. After one year, 32
percent of patients who participated in the stress management
program had lowered their A1C level by 1 percent. This kind of
reduction is significant and can greatly reduce a patient's
risk of future complications related to diabetes. Only 12
percent of the patients who received only the diabetes
education program reduced their A1C levels by that
much.
SOURCE: The 110th
annual Convention of the American Psychological Association in
Chicago, Aug. 22 - 25, 2002
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New
Transplant Technique |
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Successful kidney transplant
technique
Back to
Features |
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Researchers report high success for kidney
transplants among patients who would typically be considered
ineligible for the surgery. Researchers have treated 34
patients since 1997 with a new treatment and they say has some
surprising results. Often, patients who need a kidney
transplant are sensitized to immune system antibodies due to
previous transplants, blood transfusions or pregnancies. A new
treatment using a blood filtering process called
plasmapheresis, coupled with a drug to suppress the immune
system so patients would not reject their new organ. All of
the transplanted patients had antibodies against the donors'
HLA antigens. At the end of the treatment, nearly 80 percent
of the patients had lost antibodies against the donor organs
and 50 percent who had antibodies against other HLA antigens
had stopped producing them. After an average of 13 months
post-treatment, 92 percent of patients had no antibodies
against their donors.
SOURCE: 19th International
Congress of the Transplantation Society in Miami, Fla., Aug.
25-30, 2002
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Aspirin
& Pregnancy |
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Aspirin may help pregnancy problems
Back to
Features |
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Women at risk of developing gestational
high blood pressure may be able to reduce their risk by taking
low-dose aspirin at bedtime, according to a new study.
Researchers gave 341 women who were between 12 and 16 weeks
pregnant either an aspirin or a placebo once a day upon
awakening, eight hours after awakening, or at bedtime. All the
women were at risk for developing gestational high blood
pressure due to obesity, family history, past personal history
of gestational high blood pressure or preeclampsia or a
history of previous miscarriages. Results show there was no
difference in blood pressure between the aspirin and placebo
when taken upon awakening, but there was a considerable
reduction in blood pressure when aspirin was taken eight hours
after awakening. Blood pressure was drastically reduced in
participants who took the aspirin at bedtime. In the
group of women who took the placebo, over 14 percent had
preeclampsia, 30 percent had gestational high blood pressure,
and nearly 18 percent had pre-term labor. Of the aspirin
group, none had pre-term labor, about 7 percent had
gestational high blood pressure and only 1.7 percent had
preeclampsia.
SOURCE:
American Heart Association's 56th Annual High Blood Pressure
Convention, Orlando, Fla., Sept. 25-28,
2002
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Pain
Relief in Osteoporosis |
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Bone
cement for osteoporosis
Back to
Feature |
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Doctors have a solid solution
to relieve pain for patients who have collapsed vertebra, as a
result of osteoporosis. The procedure, vertebroplasty, has
been shown to relieve pain immediately and long-term. The
procedure uses bone cement to stabilize the collapsed
vertebra. The study involved the review of records from 100
patients, 92 of whom had compression fractures from
osteoporosis. Nearly every patient reported relief immediately
following the procedure and 93 percent reported relief that
continued long-term, which ranged from 6 to 44 months. The
researchers say patients who have these types of fractures
experience significant pain. It can limit their movement and
sometimes even require extended bed rest. They say this group
of patients can benefit greatly from pain relief. The doctors
conclude this is a minimally invasive procedure that is
beneficial to patients who have not found relief from
medication or rest.
SOURCE: Journal of Vascular
and Interventional Radiology,
2002;13:883-886
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