-In patients unable to tolerate or with a contra-indication to the use of beta-blockers, or
- In combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is > 60 bpm.
Dosage & Administration:
If the heart rate decreases persistently below 50 bpm at rest or if symptoms related to bradycardia, the dose must be adjusted downwards to 2.5mg twice daily (one half of the 5 mg tablet twice daily). Treatment must be discontinued if heart rate remains below 50 bpm or symptoms of bradycardia persist. Elderly: Consider a lower starting dose (2.5 mg twice daily i.e. one half 5 mg tablet twice daily).
Renal insufficiency: Use with caution in patients with creatinine clearance less than 15 ml/min.
Hepatic Impairment: Use with caution in patients with moderate hepatic impairment; contraindicated in severe hepatic impairment.
Children and adolescents: Not recommended.
Ivanor TM 7.5 tablet: Each box containing 10 film coated tablets in Alu-PVDC blister pack.