Dosage & Administration:
. 100 to 200 mg daily in mild conditions,
. 300 to 600 mg daily in moderately severe conditions,
. 700 to 900 mg daily in severe conditions.
If dosage on a mg/kg body weight basis is required, 2 to 10 mg/kg body weight per day should be used.
Dosage in children: Children under 15 years: 10 to 20 mg/kg body weight per day up to a maximum of 400 mg daily.
Dosage in the elderly: In the absence of specific data, the lowest dosage which produces satisfactory urate reduction should be used.
Dosage in renal impairment: In severe renal insufficiency, it may be advisable to use less than 100 mg /day or to use single doses of 100 mg at longer intervals than one day.