Ceftron®

Ceftriaxone
Cephalosporins (Penicillins and Cephalosporins)

Indication:
Ceftron® is indicated for the treatment of the following major infections when caused by
susceptible organisms: Renal and urinary tract infections, Lower respiratory tract infections,
particularly pneumonia, Gonococcal infections, Skin and soft tissue, bone and joint infections,
Bacterial meningitis, Serious bacterial infections e.g. septicemia, ENT infections, Infections in
cancer patients, Prevention of postoperative infection, Perioperative prophylaxis of infections
associated with surgery, Typhoid fever

Dosage & Administration:
Ceftron® (ceftriaxone) can be administered either intravenously or intramuscularly. When
reconstituted for intramuscular or intravenous injection, the white to yellowish-orange crystalline
powder gives a pale yellow to amber solution. Adults: The usual adult daily dose is 1-2 g once
daily, (or twice daily in equally divided doses) depending on the type and severity of infection.
The daily dose may be increased, but should not exceed 4 g. For preoperative use (surgical
prophylaxis), a single dose of 1 gm administered intravenously 0.5-2 hours before surgery is
recommended. In elderly patients, the dosages do not require modification provided that renal
and hepatic functions are satisfactory. In patients with impaired renal function, there is no need
to reduce the dosage of Ceftron®provided liver function is intact. In patients with liver damage,
there is no need for the dosage to be reduced provided renal function is intact. Gonorrhea: For
the treatment of gonorrhea (penicillinase producing and non-penicillinase producing strains), a
single intramuscular dose of 250 mg is recommended. Children under 12 years: The
recommended total daily dose is 50 to 75 mg/kg once daily (or twice daily in equally divided
doses). In severe infections, up to 80 mg/kg body weight daily may be given. The total daily dose
should not exceed 2 gm. In the treatment of meningitis, the initial dose of 100 mg/kg body
weight (not to exceed 4 gm daily) once daily (or twice daily in equally divided doses), is
recommended. As soon as the causative organism has been identified and its sensitivity, the
doses can be reduced accordingly. The usual duration of therapy in meningitis is 7 to 14 days.



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