Amistar IM/IV Injection

Amikacin Sulfate USP
Aminoglycoside (Antibiotic Preparation)

Indication:
Amikacin (Amistar) is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. Amikacin is effective in bacterial septicemia (including neonatal sepsis); in serious infections of the respiratory tract, urinary tract, bones and joints, central nervous system (including meningitis) and skin and soft tissue; intra-abdominal infections (including peritonitis); and in burns and postoperative infections (including post vascular surgery). Amikacin is also effective in infections caused by Gentamicin resistant strains of Gram-negative organisms.

Dosage & Administration:
Adults and children: 15mg/kg/day in two equally divided doses (equivalent to 500 mg bid. in adults): use of the 100mg/2ml strength is recommended for children for the accurate measurement of the appropriate dose.
Neonates and premature infants: An initial loading dose of 10mg/kg followed by 15mg/kg/day in two equally divided doses. Life-threatening infections and/or those caused by Pseudomonas: The adult dose may be increased to 500 mg every eight hours but should neither exceed 1.5g/day nor be administered for a period longer than 10 days. A maximum total adult dose of 15g should not be exceeded. Urinary tract infections (other than Pseudomonas infections): 7.5mg/kg/day in two equally divided doses (equivalent to 250 mg bid. in adults).

Preparation:
Amistar 100 IM/IV Injection: Each box contains 10 ampoules in Alu-PVC blister pack.
Amistar 500 IM/IV Injection: Each box contains 10 ampoules in Alu-PVC blister pack.



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