Seclo® MUPS

Omeprazole
Proton Pump Inhibitor (PPI) (Antiulcerant)


MUPS is abbreviation for Multiple-Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. Thus, the resulting tablets prepared by compaction of modified release coated multiparticulates or pellets are called as MUPS. It is the more recent and challenging technology that combines the advantages of both tablets and pellet-filled capsules in one dosage form.

Indication:

  • Duodenal and Gastric ulcers
  • NSAID-induced gastric and duodenal ulcers
  • Reflux Oesophagitis
  • GERD (Gastroesophageal Reflux Disease)
  • Eradication of H. pylori with appropriate antibiotics
  • Zollinger-Ellison Syndrome

Dosage & Administration:
Adults:

Indication DoseFrequency
GERD (Gastroesophageal Reflux Disease) 20 mgOnce daily for 4 weeks
Gastric ulcer 20 mgOnce daily for 4-8 weeks; in severe cases Twice daily
Duodenal ulcer 20 mgOnce daily for 2-4 weeks; in severe cases Twice daily
NSAID-induced ulceration 20 mgOnce daily for 4-8 weeks
Reflux Oesophagitis 20 mgOnce daily for 4-8 weeks; in severe cases Twice daily
H. pylori eradication (Omeprazole MUPS tablet with Amoxicillin and Clarithromycin or Metronidazole)20mg Twice daily for 1 week
Zollinger-Ellison Syndrome60mg Once daily; Usual maintenance, 20-120mg daily


Children over 2 years old:

Indication DoseFrequency
Acid regurgitation in GERD
(Gastroesophageal Reflux Disease) 		20 mgOnce daily for 2-4 weeks
Reflux Oesophagitis 20 mgOnce daily for 4-8 weeks

Preparation:
Seclo® MUPS 20 Tablet: Each box contains 30 tablets in Alu-Alu blister pack.

  • Seclo<sup>®</sup> MUPS

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