Itra^® Nova

Indication:
Itra^® Nova (Super bioavailable Itraconazole) is used for the treatment of oropharyngeal candidiasis, vulvovaginal candidiasis, pityriasis versicolor, tinea pedis, tinea cruris, tinea corporis, tinea manuum, onychomycosis and histoplasmosis. It is indicated in the treatment of systemic candidiasis, aspergillosis, and cryptococcosis (including cryptococcal meningitis). It is also used for maintenance therapy in AIDS patients to prevent relapse of underlying fungal infections and in the prevention of fungal infection during prolonged neutropenia.

Dosage & Administration:
For non-systemic fungal disease:
• Vulvovaginal candidiasis: 130 mg (2 x 65 mg capsules) twice daily for 01 day
• Pityriasis versicolor: 130 mg (2 x 65 mg capsules) twice daily for 07 days
• Tinea corporis and tinea cruris: 65 mg once daily for 15 days or 130 mg (2 x 65 mg capsules) once daily for 07 days
• Tinea pedis and tinea manuum: 65 mg once daily for 30 days
• Oropharyngeal Candidiasis: 65 mg once daily for 15 days, increase dose to 130 mg (2 x 65 mg capsules) once daily for 15 days in AIDS or neutropenic patients because of impaired absorption in these groups
• Onychomycosis (toenails with or without fingernail involvement): Either 130 mg (2 x 65 mg capsules) once daily for 3 months or course (pulse) of 130 mg (2 x 65 mg capsules) twice daily for 7 days, subsequent courses repeated after 21 day's interval. Fingernails two courses, toenails three courses.

For systemic fungal disease:
• Aspergillosis: 130 mg (2 x 65 mg capsules) once daily for 2-5 months. Increase dose to 130 mg (2 x 65 mg capsules) twice daily in case of invasive or disseminated disease
• Candidiasis: 65-130 mg once daily for 03 weeks-07 months. Increase dose to 130 mg (2 x 65 mg capsules) twice daily in case of invasive or disseminated disease
• Non-meningeal Cryptococcosis: 130 mg (2 x 65 mg capsules) once daily for 10 weeks
• Cryptococcal Meningitis: 130 mg (2 x 65 mg capsules) twice daily for 2-6 months
• Histoplasmosis: 130 mg (2 x 65 mg capsules) once daily-twice daily for 8 months
• Maintenance in AIDS: 130 mg (2 x 65 mg capsules) once daily until immune recovery
• Prophylaxis in neutropenia: 130 mg (2 x 65 mg capsules) once daily until immune recovery

The dose and duration of treatment for systemic anti-fungal disease should be adjusted depending on the clinical response.

Preparation:
Itra^® Nova 65: Each box contains 30 capsules in Alu-Alu blister pack.