D-balance^TM

Cholecalciferol EP (Vitamin D3)
Vitamin D and analogues (Plain Vitamin)

Indication:
For the prevention & treatment of Vitamin D3 & associated diseases like Osteomalacia, Rickets, Fractures, Preeclampsia, Eclampsia, during pregnancy & for the management of Cardiovascular & Diabetic profile.

Dosage & Administration:
Dosage guideline for D-balance Oral Solution:

As per ‘The Royal Children's Hospital Melbourne’ dosage guideline for Treatment and Prevention of vitamin D deficiency:

Age	Treatment of vitamin D deficiency	Prevention (maintenance dose) of vitamin D deficiency
Preterm	200 IU-800 IU /day (3 drops - 11 drops)	200 IU-400 IU/day (3drops-6 drops)
<3 months (term)	400 – 1,000 IU/day, 3 months (6 drops- 14 drops/0.5 ml)	400 IU/day (6 drops)
3–12 months	1,000-2,000 units/day, 3 months (14 drops/0.5 ml- 1 ml)	400 – 1,000 IU daily (6 drops- 14 drops/0.5 ml)

Treatment guideline for 200,000 IU Oral/IM injectable solution:
Curative measures:

Disease	Dosages (up to normalization of vitamin D level)
Rickets	1 ampoule every 2 weeks for one month then 1 ampoule for every 4 months
Osteoporosis	1 ampoule every 2 weeks for 3 months
Osteomalacia	1 ampoule every 2 weeks for 3 months
Vitamin D deficiency	1 ampoule can be repeated 1 to 6 months later

Preventive measures:

Disease	Dosages (up to normalization of vitamin D level)
Pregnacy	1/2 ampoule at 6th or 7th month
During Breast feeding	1/2 ampoule for every 6 months
Children up to 5 years	1 ampoule for every 6 months
Adolescent	1 ampoule for every 6 months
Elderly	1/2 ampoule for every 3 months

Treatment guideline for Capsule:

2000 IU Licap	Once/day (when vitamin D level is sufficient : ≥30 ng/ml or ≥ 75 nmol/L)
20000 IU Licap	Once/week for 6-10 weeks for vitamin D insufficient patients (when serum vitamin D level is 20-30 ng/mL or 50-75 nmol/L )
40000 IU Licap	Once/week for 6-10 weeks for vitamin D deficient patients (when serum vitamin D level is 12-19 ng/mL or 25-50 nmol/L )
50000 IU Licap	Once/week for 6-10 weeks for severe vitamin D deficient patients (when serum vitamin D level is <12 ng/mL or <25 nmol/L)

Dosing of capsule for Vitamin D deficiency in Children:

Vitamin D deficiency (12-18 years)	20000 IU, once every 2 weeks for 6 weeks
Prevention of Vitamin D deficiency (12-18 years)	20000 IU, once every 6 weeks

Preparation:
D-balance^TM 2000 Licap: Each Box containing 30 Licap in 30’s Alu-Alu blister pack.
D-balance^TM 20000 Licap: Each Box containing 10 Licap in 10’s Alu-Alu blister pack.
D-balance^TM 40000 Licap: Each Box containing 10 Licap in 10's Alu-Alu blister pack.
D-balance^TM 50000 Licap: Each Box containing 10 Licap in 10's Alu-Alu blister pack.
D-balance^TM 200,000 IU Oral/IM Injectable Solution : Each box contains 1 ampoule in blister pack.