Indication:
-Invasive aspergillosis in patients with disease that is refractory or intolerant to Amphotericin B or ltraconazole
-Fusariosis in patients with disease that is refractory or intolerant to Amphotericin B
-Chromoblastomycosis and mycetoma in patients with disease that is refractory or intolerant to ltraconazole
-Coccidioidomycosis in patients with disease that is refractory or intolerant to Amphotericin B, ltraconazole or Fluconazole
Also indicated for prophylaxis of invasive fungal infections in the following patients:
-Patients receiving remission-induction chemotherapy for Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndromes (MDS) and who are at high-risk of developing invasive fungal infections
-Hematopoietic Stem Cell Transplant (HSCT) recipients who are undergoing high-dose immunosuppressive therapy for graft versus host disease and who are at high-risk of developing invasive fungal infections.
Dosage & Administration:
Posaconazole Tablets can be taken with or without food.
Loading Dose: 300 mg (3 Tablets) twice a day on the first day
Maintenance Dose: 300 mg (3 Tablets) once a day from the second day
Duration of therapy should be based on the severity of the underlying disease, recovery from immunosuppression and clinical response.
Preparation:
