Fosfomax™ 4 IV Infusion

Fosfomycin 4 gm
Other Antibiotics (Other Antibiotics)

• Complicated UTI
• Hospital acquired pneumonia
• Bone and joint infections
• Bacterial meningitis
• Complicated intra-abdominal infections
• Infective endocarditis
• Complicated SSTI
• Bacteremia
Fosfomax™ 4 IV Inf. should be used only when commonly recommended antibiotics are inappropriate, or when these alternative antibacterial agents have failed to demonstrate efficacy.

Dosage & Administration:
Fosfomax™ 4 is intended for intravenous use. The duration of infusion should be at least 30 minutes.
The general dosage guidelines for adults with estimated creatinine clearance > 80 ml/min are as follows:
• Complicated urinary tract infections, Hospital-acquired pneumonia, including ventilator - associated pneumonia, Infective endocarditis, Bone and joint infections, Complicated skin and soft tissue infections, Complicated intra-abdominal infections, Bacteremia that occurs in association with, or is suspected to be associated with, any of the infections listed above: 12–24 gm in 2-3 divided doses
• Bacterial meningitis: 16–24 gm in 3-4 divided doses
Individual doses must not exceed 8g.
The dosage of Fosfomax™ 4 IV Infusion in children should be based on age and body weight.
Preparation of the solution for infusion: Fosfomax must be reconstituted and diluted prior to administration. Water for Injections and Glucose Infusion 50 mg/ml (5 %) or Glucose Infusion 100 mg/ml (10 %) may be used as solvent for the reconstitution and dilution. Sodium chloride containing solvents must not be used.
Reconstitution: Shake the vial prior to the reconstitution to loosen up the powder. Reconstitute 4 gm vials with 20 ml of solvent. Shake well to dissolve. A slight degree of warming occurs when the powder is dissolved. Transfer the reconstituted contents of 4 g vials into an infusion container with further 80 ml of solvent.

Each box contains one vial containing Fosfomycin Sodium EP with Succinic Acid sterile powder equivalent to Fosfomycin 4 gm, one 100 ml water for injection in PP bottle, one 20 ml disposable syringe and one infusion set with butterfly needle.

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